Synthetic Methods for the Preparation of Platinum Anticancer Complexes
نویسندگان
چکیده
منابع مشابه
Synthetic methods for the preparation of platinum anticancer complexes.
The demonstration in the 1960's that cis-diamminedichloroplatinum(II), or cisplatin, inhibits cellular division of Escherichia coli1 led to the subsequent discovery that this simple coordination compound is also an effective antitumor agent in mouse models.2 Subsequent studies validated cisplatin as an effective anticancer agent in humans as well,3–7 and FDA approval of cisplatin for the treatm...
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A wide range of research activities have been carried out so far on benzimidazole and pyridine derivatives to evaluate their Antiviral, Anticancer, Anticonvulsant, Anthelmintic Activity and many promising results are obtained with respect to the anticancer activity. Out of the various ligands used, the alkylating agents are found to be highly active with respect to cancer chemotherapy. Nitrogen...
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ژورنال
عنوان ژورنال: Chemical Reviews
سال: 2013
ISSN: 0009-2665,1520-6890
DOI: 10.1021/cr4004314